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IZH4 Izh4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854052, updated on 19-Mar-2019

Summary

Gene symbol
IZH4
Gene description
Izh4p
Primary source
SGD:S000005461
Locus tag
YOL101C
Gene type
protein coding
RNA name
Izh4p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See IZH4 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (126982..127920, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene myo-inositol transporter ITR2 Neighboring gene tRNA 2'-phosphotransferase Neighboring gene serine/threonine protein kinase PKH2 Neighboring gene Sdd3p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cellular zinc ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular zinc ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm HDA PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
fungal-type vacuole HDA PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus HDA PubMed 

General protein information

Preferred Names
Izh4p
NP_014540.1
  • Membrane protein involved in zinc ion homeostasis; member of the four-protein IZH family; expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism; protein increases in abundance and relocalizes from nucleus to ER upon DNA replication stress; IZH4 has a paralog, IZH1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    126982..127920 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183355.1NP_014540.1  TPA: Izh4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014540.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q99393
    Conserved Domains (1) summary
    cl03831
    Location:27298
    HlyIII; Haemolysin-III related
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