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PAP2 non-canonical poly(A) polymerase PAP2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854034, updated on 5-Sep-2021

Summary

Gene symbol
PAP2
Gene description
non-canonical poly(A) polymerase PAP2
Primary source
SGD:S000005475
Locus tag
YOL115W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
TRF4
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Genomic context

See PAP2 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (101475..103229)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Rri2p Neighboring gene Msn1p Neighboring gene Pth4p Neighboring gene putative serine/threonine protein kinase SKM1

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Process Evidence Code Pubs
involved_in RNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in U4 snRNA 3'-end processing IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in U4 snRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in base-excision repair IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in base-excision repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in histone mRNA catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in meiotic DNA double-strand break formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ncRNA polyadenylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in ncRNA polyadenylation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in ncRNA polyadenylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of DNA recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in nuclear mRNA surveillance of mRNA 3'-end processing IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in nuclear polyadenylation-dependent CUT catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in nuclear polyadenylation-dependent CUT catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in nuclear polyadenylation-dependent antisense transcript catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in nuclear polyadenylation-dependent mRNA catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in nuclear polyadenylation-dependent rRNA catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in nuclear polyadenylation-dependent rRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in nuclear polyadenylation-dependent snRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in nuclear polyadenylation-dependent snoRNA catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in nuclear polyadenylation-dependent snoRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in nuclear polyadenylation-dependent tRNA catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in nuclear polyadenylation-dependent tRNA catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in nuclear polyadenylation-dependent tRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in polyadenylation-dependent mRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in polyadenylation-dependent snoRNA 3'-end processing IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in sno(s)RNA polyadenylation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in tRNA modification IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of TRAMP complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of TRAMP complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
non-canonical poly(A) polymerase PAP2
NP_014526.1
  • Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of TRAMP; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; required for mRNA surveillance and maintenance of genome integrity, serving as a link between RNA and DNA metabolism; overlapping but non-redundant functions with Trf5p; relocalizes to cytosol in response to hypoxia

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    101475..103229
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183369.1NP_014526.1  TPA: non-canonical poly(A) polymerase PAP2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014526.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53632
    Conserved Domains (1) summary
    COG5260
    Location:116584
    TRF4; DNA polymerase sigma [Replication, recombination and repair]
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