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RIB4 lumazine synthase RIB4 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854022, updated on 9-Aug-2022

Summary

Gene symbol
RIB4
Gene description
lumazine synthase RIB4
Primary source
SGD:S000005503
Locus tag
YOL143C
See related
AllianceGenome:SGD:S000005503
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables 6,7-dimethyl-8-ribityllumazine synthase activity. Involved in riboflavin biosynthetic process. Located in mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See RIB4 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (54595..55104, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Ctr9p Neighboring gene Nop8p Neighboring gene exosome non-catalytic core subunit RRP40 Neighboring gene tRNA methyltransferase PPM2

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables 6,7-dimethyl-8-ribityllumazine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables 6,7-dimethyl-8-ribityllumazine synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 6,7-dimethyl-8-ribityllumazine synthase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in riboflavin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in riboflavin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in riboflavin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in intracellular anatomical structure IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in mitochondrial intermembrane space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrial intermembrane space IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrial intermembrane space IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus HDA PubMed 
part_of riboflavin synthase complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
lumazine synthase RIB4
NP_014498.1
  • Lumazine synthase (DMRL synthase); catalyzes synthesis of immediate precursor to riboflavin; DMRL synthase stands for 6,7-dimethyl-8-ribityllumazine synthase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    54595..55104 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183397.1NP_014498.1  TPA: lumazine synthase RIB4 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014498.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P50861, Q08286
    UniProtKB/TrEMBL
    A0A6A5Q2Y9, G2WM95, N1NVR4
    Conserved Domains (1) summary
    TIGR00114
    Location:18164
    lumazine-synth; 6,7-dimethyl-8-ribityllumazine synthase