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DAD2 Dad2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853958, updated on 5-Nov-2017
Gene symbol
DAD2
Gene description
Dad2p
Primary source
SGD:S000001791
Locus tag
YKR083C
Gene type
protein coding
RNA name
Dad2p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HSK1
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (596421..596822, complement)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene rRNA-binding ribosome biosynthesis protein RPF2 Neighboring gene Nup133p Neighboring gene ribosome dissociation factor GTPase HBS1 Neighboring gene mitochondrial 54S ribosomal protein YmL20

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
contributes_to microtubule binding IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to microtubule plus-end binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
attachment of spindle microtubules to kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
chromosome segregation IEA
Inferred from Electronic Annotation
more info
 
mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
mitotic sister chromatid biorientation IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of attachment of spindle microtubules to kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of microtubule polymerization IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
DASH complex IDA
Inferred from Direct Assay
more info
PubMed 
DASH complex IEA
Inferred from Electronic Annotation
more info
 
chromosome IEA
Inferred from Electronic Annotation
more info
 
chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 
condensed chromosome kinetochore IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
kinetochore IEA
Inferred from Electronic Annotation
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
mitotic spindle IEA
Inferred from Electronic Annotation
more info
 
mitotic spindle midzone IBA
Inferred from Biological aspect of Ancestor
more info
 
mitotic spindle pole body IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
spindle IEA
Inferred from Electronic Annotation
more info
 
Names
Dad2p
NP_013009.1
  • Essential subunit of the Dam1 complex (aka DASH complex); complex couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    596421..596822 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179873.1NP_013009.1  TPA: Dad2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013009.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P36162
    Conserved Domains (1) summary
    pfam08654
    Location:6129
    DASH_Dad2; DASH complex subunit Dad2
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