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UTH1 SUN family protein UTH1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853916, updated on 22-Sep-2022

Summary

Gene symbol
UTH1
Gene description
SUN family protein UTH1
Primary source
SGD:S000001750
Locus tag
YKR042W
See related
AllianceGenome:SGD:S000001750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable hydrolase activity, acting on glycosyl bonds. Involved in autophagy of mitochondrion and fungal-type cell wall biogenesis. Is extrinsic component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See UTH1 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (519527..520624)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene tRNA-Ala Neighboring gene uncharacterized protein Neighboring gene sedoheptulose-bisphosphatase Neighboring gene Uip5p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
 
involved_in autophagy of mitochondrion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
 
involved_in division septum assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in fungal-type cell wall biogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fungal-type cell wall organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in polysaccharide catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in fungal-type cell wall IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
SUN family protein UTH1
NP_012968.4
  • Mitochondrial inner membrane protein; role in mitophagy is disputed; implicated in cell wall biogenesis, the oxidative stress response, life span during starvation, and cell death; SUN family member; UTH1 has a paralog, NCA3, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    519527..520624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179832.3NP_012968.4  TPA: SUN family protein UTH1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012968.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXA4, P36135
    UniProtKB/TrEMBL
    A0A8H4BZ52, G2WI71, N1P0X3
    Conserved Domains (1) summary
    pfam03856
    Location:111352
    SUN; Beta-glucosidase (SUN family)