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CAP1 Cap1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853862, updated on 8-Jun-2019

Summary

Gene symbol
CAP1
Gene description
Cap1p
Primary source
SGD:S000001490
Locus tag
YKL007W
Gene type
protein coding
RNA name
Cap1p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See CAP1 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (429302..430108)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Mrt4p Neighboring gene sphingosine N-acyltransferase LAC1 Neighboring gene Sft1p Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the CAP1 gene: The CAP1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, S.cerevisiae, K.lactis, E.gossypii, M.oryzae, N.crassa, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
actin binding IEA
Inferred from Electronic Annotation
more info
 
actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin filament binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin filament capping IEA
Inferred from Electronic Annotation
more info
 
barbed-end actin filament capping IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
barbed-end actin filament capping IDA
Inferred from Direct Assay
more info
PubMed 
barbed-end actin filament capping IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
F-actin capping protein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
F-actin capping protein complex IDA
Inferred from Direct Assay
more info
PubMed 
F-actin capping protein complex IEA
Inferred from Electronic Annotation
more info
 
F-actin capping protein complex IMP
Inferred from Mutant Phenotype
more info
PubMed 
actin cortical patch IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin cortical patch IDA
Inferred from Direct Assay
more info
PubMed 
cellular bud neck HDA PubMed 
cellular bud tip HDA PubMed 
cellular bud tip IDA
Inferred from Direct Assay
more info
PubMed 
incipient cellular bud site IDA
Inferred from Direct Assay
more info
PubMed 
mating projection tip HDA PubMed 
plasma membrane HDA PubMed 

General protein information

Preferred Names
Cap1p
NP_012918.1
  • Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p); capping protein (CP) binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches; protein increases in abundance and relocalizes from bud neck to plasma membrane upon DNA replication stress

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    429302..430108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179573.1NP_012918.1  TPA: Cap1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012918.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P28495
    Conserved Domains (1) summary
    pfam01267
    Location:10265
    F-actin_cap_A; F-actin capping protein alpha subunit
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