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TOA2 transcription initiation factor IIA subunit gamma [ Saccharomyces cerevisiae S288C ]

Gene ID: 853807, updated on 11-Jun-2025
Official Symbol
TOA2
Official Full Name
transcription initiation factor IIA subunit gamma
Primary source
SGD:S000001541
Locus tag
YKL058W
See related
AllianceGenome:SGD:S000001541; FungiDB:YKL058W; VEuPathDB:YKL058W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Contributes to TBP-class protein binding activity. Involved in RNA polymerase II preinitiation complex assembly. Part of transcription factor TFIIA complex. Orthologous to human GTF2A2 (general transcription factor IIA subunit 2). [provided by Alliance of Genome Resources, Jun 2025]
Orthologs
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Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (330166..330534)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene fructose-bisphosphate aldolase FBA1 Neighboring gene cleavage polyadenylation factor subunit MPE1 Neighboring gene Nup120p Neighboring gene Tma19p

Genomic Sequence:
NC_001143.9
Products Interactant Other Gene Complex Source Pubs Description
Preferred Names
transcription initiation factor IIA subunit gamma
NP_012865.1
  • TFIIA small subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; required, along with Toa1p, for ribosomal protein gene transcription in vivo; homologous to smallest subunit of human and Drosophila TFIIA; protein abundance increases in response to DNA replication stress

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    330166..330534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179624.1NP_012865.1  TPA: transcription initiation factor IIA subunit gamma [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012865.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXM9, P32774
    UniProtKB/TrEMBL
    A6ZZQ8, B3LR33, C7GP16, C8ZCB4, G2WHX4, N1P094
    Conserved Domains (1) summary
    COG5123
    Location:3122
    TOA2; Transcription initiation factor IIA, gamma subunit [Transcription]