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DAN1 Dan1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853615, updated on 3-May-2025
Official Symbol
DAN1
Official Full Name
Dan1p
Primary source
SGD:S000003911
Locus tag
YJR150C
See related
AllianceGenome:SGD:S000003911; FungiDB:YJR150C; VEuPathDB:YJR150C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CCW13
Summary
Predicted to be a structural constituent of cell wall. Involved in sterol transport. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, May 2025]
Orthologs
all
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See DAN1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (708811..709707, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene branched-chain-amino-acid transaminase BAT2 Neighboring gene putative nitronate monooxygenase Neighboring gene Dan4p Neighboring gene uncharacterized protein

Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Engineering promoter regulation. Nevoigt E, et al. Biotechnol Bioeng, 2007 Feb 15. PMID 16964624
  2. SUT1-promoted sterol uptake involves the ABC transporter Aus1 and the mannoprotein Dan1 whose synergistic action is sufficient for this process. Alimardani P, et al. Biochem J, 2004 Jul 1. PMID 15035656, Free PMC Article
  3. Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. Wilcox LJ, et al. J Biol Chem, 2002 Sep 6. PMID 12077145
  4. The DAN1 gene of S. cerevisiae is regulated in parallel with the hypoxic genes, but by a different mechanism. Sertil O, et al. Gene, 1997 Jun 19. PMID 9224891
  5. Induction of DAN/TIR yeast cell wall mannoprotein genes in response to high hydrostatic pressure and low temperature. Abe F. FEBS Lett, 2007 Oct 16. PMID 17910955

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables structural constituent of cell wall IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in fungal-type cell wall organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sterol transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in fungal-type cell wall IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in fungal-type cell wall IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
Dan1p
NP_012684.4
  • Cell wall mannoprotein; has similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    708811..709707 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181808.4 → NP_012684.4  TPA: Dan1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012684.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VWW8, O94102, P47178
    UniProtKB/TrEMBL
    A6ZQA6, B3LQM9, B5VLT7, G2WHF2, N1P1V2
    Conserved Domains (1) summary
    pfam00660
    Location:25 → 117
    SRP1_TIP1; Seripauperin and TIP1 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P47178.2

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