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EFM3 protein-lysine N-methyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 853593, updated on 5-Aug-2018

Summary

Gene symbol
EFM3
Gene description
protein-lysine N-methyltransferase
Primary source
SGD:S000003890
Locus tag
YJR129C
Gene type
protein coding
RNA name
protein-lysine N-methyltransferase
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See EFM3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (664000..665019, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Rsf2p Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene cystathionine gamma-synthase Neighboring gene mannosyl-oligosaccharide 1,2-alpha-mannosidase

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
protein-lysine N-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
methylation IEA
Inferred from Electronic Annotation
more info
 
peptidyl-lysine trimethylation IDA
Inferred from Direct Assay
more info
PubMed 
peptidyl-lysine trimethylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm HDA PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein-lysine N-methyltransferase
NP_012663.2
  • S-adenosylmethionine-dependent methyltransferase; seven-beta-strand lysine methyltransferase which trimethylates translation elongation factor EF2 (Eft1p and Eft2p) at lysine 509; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; ortholog of human gene FAM86A

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    664000..665019 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181787.2NP_012663.2  TPA: protein-lysine N-methyltransferase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012663.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P47163
    Conserved Domains (1) summary
    cl17173
    Location:137286
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
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