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SSC1 Hsp70 family ATPase SSC1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853503, updated on 29-Mar-2020

Summary

Gene symbol
SSC1
Gene description
Hsp70 family ATPase SSC1
Primary source
SGD:S000003806
Locus tag
YJR045C
Gene type
protein coding
RNA name
Hsp70 family ATPase SSC1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ENS1

Genomic context

See SSC1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (519638..521602, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Neighboring gene Vps55p Neighboring gene Tah11p Neighboring gene

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the SSC1 gene: The SSC1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
enzyme regulator activity IDA
Inferred from Direct Assay
more info
PubMed 
heat shock protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding involved in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular response to unfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of endodeoxyribonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
protein folding IEA
Inferred from Electronic Annotation
more info
 
protein import into mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
protein import into mitochondrial matrix IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein refolding IDA
Inferred from Direct Assay
more info
PubMed 
protein refolding IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein unfolding IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to unfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
PAM complex, Tim23 associated import motor IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 
mitochondrial nucleoid IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion HDA PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Hsp70 family ATPase SSC1
NP_012579.1
  • Hsp70 family ATPase; constituent of the import motor component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in protein translocation and folding; subunit of SceI endonuclease; SSC1 has a paralog, ECM10, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    519638..521602 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181703.1NP_012579.1  TPA: Hsp70 family ATPase SSC1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012579.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P0CS90
    Conserved Domains (2) summary
    cd11733
    Location:29405
    HSPA9-like_NBD; Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins
    PRK00290
    Location:30633
    dnaK; molecular chaperone DnaK; Provisional
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