Format

Send to:

Choose Destination

ESS1 peptidylprolyl isomerase ESS1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853475, updated on 5-Nov-2017
Gene symbol
ESS1
Gene description
peptidylprolyl isomerase ESS1
Primary source
SGD:S000003778
Locus tag
YJR017C
Gene type
protein coding
RNA name
peptidylprolyl isomerase ESS1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
PIN1; PTF1
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (466521..467033, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene dihydroxy-acid dehydratase ILV3 Neighboring gene Tes1p Neighboring gene Rec107p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
RNA polymerase II core binding IPI
Inferred from Physical Interaction
more info
PubMed 
isomerase activity IEA
Inferred from Electronic Annotation
more info
 
peptidyl-prolyl cis-trans isomerase activity IDA
Inferred from Direct Assay
more info
PubMed 
peptidyl-prolyl cis-trans isomerase activity IEA
Inferred from Electronic Annotation
more info
 
peptidyl-prolyl cis-trans isomerase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
histone H3-K4 trimethylation IGI
Inferred from Genetic Interaction
more info
PubMed 
histone H3-K4 trimethylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of histone deacetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of histone deacetylation IPI
Inferred from Physical Interaction
more info
PubMed 
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of chromatin silencing at rDNA IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of protein dephosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IPI
Inferred from Physical Interaction
more info
PubMed 
protein peptidyl-prolyl isomerization IDA
Inferred from Direct Assay
more info
PubMed 
protein peptidyl-prolyl isomerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of phosphorylation of RNA polymerase II C-terminal domain IDA
Inferred from Direct Assay
more info
PubMed 
termination of RNA polymerase II transcription IGI
Inferred from Genetic Interaction
more info
PubMed 
termination of RNA polymerase II transcription IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IC
Inferred by Curator
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
peptidylprolyl isomerase ESS1
NP_012551.2
  • Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated S/T residues N-terminal to proline; regulates phosphorylation of RNAPII large subunit (Rpo21p) C-terminal domain (CTD) at Ser7; associates with phospho-Ser5 form of RNAPII in vivo; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription, trimethylation of histone H3; human ortholog PIN1 can complement yeast null and ts mutants

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    466521..467033 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181675.1NP_012551.2  TPA: peptidylprolyl isomerase ESS1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012551.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P22696
    Conserved Domains (3) summary
    smart00456
    Location:1043
    WW; Domain with 2 conserved Trp (W) residues
    COG0760
    Location:1167
    SurA; Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]
    cl08278
    Location:59170
    Rotamase_2; PPIC-type PPIASE domain
Support Center