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SYS1 Sys1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853453, updated on 13-Apr-2024

Summary

Gene symbol
SYS1
Gene description
Sys1p
Primary source
SGD:S000003541
Locus tag
YJL004C
See related
AllianceGenome:SGD:S000003541
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in Golgi to endosome transport; Golgi to plasma membrane protein transport; and protein localization to Golgi apparatus. Located in trans-Golgi network. Is integral component of Golgi membrane. Orthologous to human SYS1 (SYS1 golgi trafficking protein). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (431589..432200, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene tRNA-Leu Neighboring gene adenylate cyclase Neighboring gene Cox16p Neighboring gene dolichyl-diphosphooligosaccharide--protein glycotransferase subunit OST1

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in Golgi to endosome transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in Golgi to endosome transport IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in Golgi to plasma membrane protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in Golgi to plasma membrane protein transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein localization to Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein localization to Golgi apparatus IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in trans-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Sys1p
NP_012530.1
  • Integral membrane protein of the Golgi; required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    431589..432200 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181438.1NP_012530.1  TPA: Sys1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012530.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VWH1, P41544
    UniProtKB/TrEMBL
    A0A6A5PWU1, A6ZPW3, B3LQ95, C7GUU3, D3UF65, G2WH06, N1P8L1
    Conserved Domains (1) summary
    pfam09801
    Location:20163
    SYS1; Integral membrane protein S linking to the trans Golgi network