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JEM1 Jem1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853372, updated on 5-Aug-2018

Summary

Gene symbol
JEM1
Gene description
Jem1p
Primary source
SGD:S000003609
Locus tag
YJL073W
Gene type
protein coding
RNA name
Jem1p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
KAR8

Genomic context

See JEM1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (303181..305118)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Net1p Neighboring gene cohesin subunit SMC3 Neighboring gene DNA replication protein PSF2 Neighboring gene acetyl-CoA:L-glutamate N-acetyltransferase

Pathways from BioSystems

  • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
  • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
chaperone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chaperone binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
unfolded protein binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
karyogamy involved in conjugation with cellular fusion IGI
Inferred from Genetic Interaction
more info
PubMed 
karyogamy involved in conjugation with cellular fusion IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein folding in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein folding in endoplasmic reticulum IGI
Inferred from Genetic Interaction
more info
PubMed 
ubiquitin-dependent ERAD pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum HDA PubMed 
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear outer membrane-endoplasmic reticulum membrane network IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Jem1p
NP_012462.3
  • DnaJ-like chaperone required for nuclear membrane fusion during mating; localizes to the ER membrane; exhibits genetic interactions with KAR2

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    303181..305118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181506.3NP_012462.3  TPA: Jem1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012462.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P40358
    Conserved Domains (2) summary
    COG0484
    Location:536644
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    pfam00226
    Location:538605
    DnaJ; DnaJ domain
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