Format

Send to:

Choose Destination

LSM1 Lsm1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853318, updated on 5-Sep-2021

Summary

Gene symbol
LSM1
Gene description
Lsm1p
Primary source
SGD:S000003660
Locus tag
YJL124C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SPB8
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See LSM1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (187126..187644, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene putative hydrolase Neighboring gene tRNA 1-methyladenosine methyltransferase subunit GCD14 Neighboring gene Mtc1p Neighboring gene Alb1p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the LSM1 gene: The LSM1 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA cap binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA cap binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of Lsm1-7-Pat1 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of Lsm1-7-Pat1 complex IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in P-body IDA
Inferred from Direct Assay
more info
PubMed 
located_in P-body IEA
Inferred from Electronic Annotation
more info
 
located_in P-body IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in cytoplasm HDA PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Lsm1p
NP_012411.1
  • Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; also enters the nucleus and positively regulates transcription initiation; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; binds to mRNAs under glucose starvation, most often in the 3' UTR; forms cytoplasmic foci upon DNA replication stress

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    187126..187644 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181557.1NP_012411.1  TPA: Lsm1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012411.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P47017
    Conserved Domains (1) summary
    cd01728
    Location:40115
    LSm1; Like-Sm protein 1
Support Center