U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 853276, updated on 24-Jan-2026
Official Full Name
uncharacterized protein
Primary source
SGD:S000003699
Locus tag
YJL163C
See related
AllianceGenome:SGD:S000003699; FungiDB:YJL163C; VEuPathDB:YJL163C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in fungal-type vacuole membrane. Human ortholog(s) of this gene implicated in hereditary folate malabsorption. Orthologous to human SLC46A1 (solute carrier family 46 member 1); SLC46A2 (solute carrier family 46 member 2); and SLC46A3 (solute carrier family 46 member 3). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (111666..113333, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene protein kinase HAL5 Neighboring gene cAMP-dependent protein kinase catalytic subunit TPK1 Neighboring gene Jjj2p Neighboring gene tRNA-Glu

Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cross-linking Mass Spectrometry Analysis of the Yeast Nucleus Reveals Extensive Protein-Protein Interactions Not Detected by Systematic Two-Hybrid or Affinity Purification-Mass Spectrometry. Bartolec TK, et al. Anal Chem, 2020 Jan 21. PMID 31851481
  2. Whi3, a developmental regulator of budding yeast, binds a large set of mRNAs functionally related to the endoplasmic reticulum. Colomina N, et al. J Biol Chem, 2008 Oct 17. PMID 18667435, Free PMC Article
  3. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. Galibert F, et al. EMBO J, 1996 May 1. PMID 8641269, Free PMC Article
  4. A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export. Oliete-Calvo P, et al. EMBO Rep, 2018 Nov. PMID 30249596, Free PMC Article
  5. Large-scale identification of yeast integral membrane protein interactions. Miller JP, et al. Proc Natl Acad Sci U S A, 2005 Aug 23. PMID 16093310, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in fungal-type vacuole membrane HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
uncharacterized protein

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    111666..113333 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181596.1 → NP_012372.1  uncharacterized protein

    See identical proteins and their annotated locations for NP_012372.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VW24, P46996
    UniProtKB/TrEMBL
    A6ZQG9, C8ZB56, N1P1Y0
    Conserved Domains (1) summary
    cl28910
    Location:139 → 545
    MFS; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P46996.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.