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QCR8 ubiquinol--cytochrome-c reductase subunit 8 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853273, updated on 18-Sep-2024

Summary

Official Symbol
QCR8
Official Full Name
ubiquinol--cytochrome-c reductase subunit 8
Primary source
SGD:S000003702
Locus tag
YJL166W
See related
AllianceGenome:SGD:S000003702; FungiDB:YJL166W; VEuPathDB:YJL166W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
COR5
Summary
Enables ubiquinol-cytochrome-c reductase activity. Involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. Part of mitochondrial respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 4. Orthologous to human UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See QCR8 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (106434..106718)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene histone methyltransferase SET2 Neighboring gene bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase Neighboring gene protein kinase HAL5 Neighboring gene cAMP-dependent protein kinase catalytic subunit TPK1

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
ubiquinol--cytochrome-c reductase subunit 8
NP_012369.1
  • Subunit 8 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    106434..106718
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181599.1NP_012369.1  TPA: ubiquinol--cytochrome-c reductase subunit 8 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012369.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VW21, P08525
    UniProtKB/TrEMBL
    A6ZQG6, B3LPV7, C7GRZ4, C8ZB53, G2WGK7, N1P3U7
    Conserved Domains (1) summary
    pfam02939
    Location:1289
    UcrQ; UcrQ family