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KRE9 Kre9p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853265, updated on 19-Nov-2025
Official Symbol
KRE9
Official Full Name
Kre9p
Primary source
SGD:S000003710
Locus tag
YJL174W
See related
AllianceGenome:SGD:S000003710; FungiDB:YJL174W; VEuPathDB:YJL174W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in (1->6)-beta-D-glucan metabolic process and fungal-type cell wall organization. Located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See KRE9 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (95092..95922)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein uL22 RPL17B Neighboring gene Swi3p Neighboring gene Rfa3p Neighboring gene Gly-Xaa carboxypeptidase

Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. SKN7, a yeast multicopy suppressor of a mutation affecting cell wall beta-glucan assembly, encodes a product with domains homologous to prokaryotic two-component regulators and to heat shock transcription factors. Brown JL, et al. J Bacteriol, 1993 Nov. PMID 8226633, Free PMC Article
  2. The KNH1 gene of Saccharomyces cerevisiae is a functional homolog of KRE9. Dijkgraaf GJ, et al. Yeast, 1996 Jun 15. PMID 8810042
  3. Yeast Skn7p functions in a eukaryotic two-component regulatory pathway. Brown JL, et al. EMBO J, 1994 Nov 1. PMID 7957083, Free PMC Article
  4. Genetic, biochemical, and morphological evidence for the involvement of N-glycosylation in biosynthesis of the cell wall beta1,6-glucan of Saccharomyces cerevisiae. Chavan M, et al. Proc Natl Acad Sci U S A, 2003 Dec 23. PMID 14676317, Free PMC Article
  5. The yeast KRE9 gene encodes an O glycoprotein involved in cell surface beta-glucan assembly. Brown JL, et al. Mol Cell Biol, 1993 Oct. PMID 8413233, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in (1->6)-beta-D-glucan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in (1->6)-beta-D-glucan biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in (1->6)-beta-D-glucan metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cell wall biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
  
involved_in fungal-type cell wall organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fungal-type cell wall organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in fungal-type vacuole HDA PubMed 
Preferred Names
Kre9p
NP_012361.1
  • Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to severe growth defects, aberrant multibudded morphology, and mating defects

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    95092..95922
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181607.1 → NP_012361.1  TPA: Kre9p

    See identical proteins and their annotated locations for NP_012361.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VW14, P39005
    UniProtKB/TrEMBL
    A0A0L8VMS8, A6ZQF9, B3LPV0, B5VL14, C7GS01, C8ZB45, G2WGK0
    Conserved Domains (2) summary
    pfam10342
    Location:27 → 133
    GPI-anchored; Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family
    pfam05390
    Location:173 → 273
    KRE9; Yeast cell wall synthesis protein KRE9/KNH1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P39005.1

Gene LinkOut

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