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SWI3 Swi3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853264, updated on 9-Dec-2017
Gene symbol
SWI3
Gene description
Swi3p
Primary source
SGD:S000003712
Locus tag
YJL176C
Gene type
protein coding
RNA name
Swi3p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HAF2; TYE2
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (92053..94530, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Atg27p Neighboring gene ribosomal 60S subunit protein L17B Neighboring gene Kre9p Neighboring gene Rfa3p

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
contributes_to DNA translocase activity IDA
Inferred from Direct Assay
more info
PubMed 
histone binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
SWI/SNF complex IDA
Inferred from Direct Assay
more info
PubMed 
SWI/SNF complex IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Swi3p
NP_012359.1
  • Subunit of the SWI/SNF chromatin remodeling complex; SWI/SNF regulates transcription by remodeling chromosomes; contains SANT domain that is required for SWI/SNF assembly; is essential for displacement of histone H2A-H2B dimers during ATP-dependent remodeling; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; relocates to the cytosol under hypoxic conditions

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    92053..94530 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181609.1NP_012359.1  TPA: Swi3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012359.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P32591
    Conserved Domains (4) summary
    COG5259
    Location:253825
    RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
    cd00167
    Location:526568
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam04433
    Location:308393
    SWIRM; SWIRM domain
    pfam16495
    Location:659741
    SWIRM-assoc_1; SWIRM-associated region 1
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