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ZUO1 zuotin [ Saccharomyces cerevisiae S288C ]

Gene ID: 853202, updated on 18-Apr-2019

Summary

Gene symbol
ZUO1
Gene description
zuotin
Primary source
SGD:S000003517
Locus tag
YGR285C
Gene type
protein coding
RNA name
zuotin
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See ZUO1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (1061852..1063153, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene putative methyltransferase Neighboring gene Erv29p Neighboring gene biotin synthase Neighboring gene oligo-1,6-glucosidase IMA1

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the ZUO1 gene: The ZUO1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
ribosome binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
'de novo' cotranslational protein folding IMP
Inferred from Mutant Phenotype
more info
PubMed 
rRNA processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of translational fidelity IMP
Inferred from Mutant Phenotype
more info
PubMed 
ribosomal subunit export from nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 
translational frameshifting IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm HDA PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
mitochondrion HDA PubMed 
nucleolus IMP
Inferred from Mutant Phenotype
more info
PubMed 
polysome IDA
Inferred from Direct Assay
more info
PubMed 
ribosome IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zuotin
NP_011801.1
  • Ribosome-associated chaperone; zuotin functions in ribosome biogenesis and as a chaperone for nascent polypeptide chains in partnership with Ssz1p and SSb1/2; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p; human gene DNAJC2 can partially complement yeast zuo1 null mutant

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    1061852..1063153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181414.1NP_011801.1  TPA: zuotin [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011801.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P32527
    Conserved Domains (3) summary
    COG5269
    Location:50433
    ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
    pfam00226
    Location:97165
    DnaJ; DnaJ domain
    pfam16717
    Location:357425
    RAC_head; Ribosome-associated complex head domain
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