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PAQR8 progestin and adipoQ receptor family member 8 [ Homo sapiens (human) ]

Gene ID: 85315, updated on 2-Oct-2018

Summary

Official Symbol
PAQR8provided by HGNC
Official Full Name
progestin and adipoQ receptor family member 8provided by HGNC
Primary source
HGNC:HGNC:15708
See related
Ensembl:ENSG00000170915 MIM:607780; Vega:OTTHUMG00000014846
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MPRB; LMPB1; C6orf33
Expression
Broad expression in brain (RPKM 26.8), colon (RPKM 23.1) and 21 other tissues See more
Orthologs

Genomic context

See PAQR8 in Genome Data Viewer
Location:
6p12.2
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 6 NC_000006.12 (52362128..52407777)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (52226926..52272575)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 20 pseudogene 1 Neighboring gene minichromosome maintenance complex component 3 Neighboring gene VISTA enhancer hs2064 Neighboring gene EF-hand domain containing 1 Neighboring gene translocation associated membrane protein 2 Neighboring gene uncharacterized LOC107986603

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

General gene information

Markers

Potential readthrough

Included gene: EFHC1

Homology

Clone Names

  • FLJ32521, FLJ46206

Gene Ontology Provided by GOA

Function Evidence Code Pubs
signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
steroid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
oogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
membrane progestin receptor beta
Names
lysosomal membrane protein in brain-1
mPR beta
membrane progesterone P4 receptor beta
membrane progesterone receptor beta
progesterone and adipoQ receptor family member 8
progestin and adipoQ receptor family member VIII

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133367.4NP_588608.1  membrane progestin receptor beta

    See identical proteins and their annotated locations for NP_588608.1

    Status: VALIDATED

    Source sequence(s)
    AF347029, AI655504, AI656485, AK128085, BC030664, CD672455, CN283490, CN395844
    Consensus CDS
    CCDS4941.1
    UniProtKB/Swiss-Prot
    Q8TEZ7
    UniProtKB/TrEMBL
    B3KXW6
    Related
    ENSP00000406197.2, OTTHUMP00000016604, ENST00000442253.2, OTTHUMT00000040903
    Conserved Domains (1) summary
    pfam03006
    Location:70297
    HlyIII; Haemolysin-III related

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p12 Primary Assembly

    Range
    52362128..52407777
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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