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QCR9 ubiquinol--cytochrome-c reductase subunit 9 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853095, updated on 6-Jul-2026
Official Symbol
QCR9
Official Full Name
ubiquinol--cytochrome-c reductase subunit 9
Primary source
SGD:S000003415
Locus tag
YGR183C
See related
AllianceGenome:SGD:S000003415; FungiDB:YGR183C; VEuPathDB:YGR183C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
UCR9
Summary
Contributes to ubiquinol-cytochrome-c reductase activity. Involved in mitochondrial electron transport, ubiquinol to cytochrome c and mitochondrial respiratory chain complex III assembly. Located in mitochondrion. Part of respiratory chain complex III. Orthologous to human UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
all
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See QCR9 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
2
Sequence:
Chromosome: VII; NC_001139.9 (859063..859476, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene tRNA-Leu Neighboring gene protein translocase subunit TIM13 Neighboring gene E3 ubiquitin-protein ligase UBR1 Neighboring gene tyrosine--tRNA ligase TYS1

Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Deletion of subunit 9 of the Saccharomyces cerevisiae cytochrome bc1 complex specifically impairs electron transfer at the ubiquinol oxidase site (center P) in the bc1 complex. Graham LA, et al. FEBS Lett, 1992 Nov 30. PMID 1332881
  2. Isolation and characterization of QCR9, a nuclear gene encoding the 7.3-kDa subunit 9 of the Saccharomyces cerevisiae ubiquinol-cytochrome c oxidoreductase complex. An intron-containing gene with a conserved sequence occurring in the intron of COX4. Phillips JD, et al. J Biol Chem, 1990 Dec 5. PMID 2174427
  3. Subunit 9 of the Saccharomyces cerevisiae cytochrome bc1 complex is required for insertion of EPR-detectable iron-sulfur cluster into the Rieske iron-sulfur protein. Phillips JD, et al. J Biol Chem, 1993 Jun 5. PMID 8389362
  4. A pathogenic cytochrome b mutation reveals new interactions between subunits of the mitochondrial bc1 complex. Saint-Georges Y, et al. J Biol Chem, 2002 Dec 20. PMID 12384503
  5. Enhanced hexose fermentation by Saccharomyces cerevisiae through integration of stoichiometric modeling and genetic screening. Quarterman J, et al. J Biotechnol, 2015 Jan 20. PMID 25435378

See all (80) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to quinol-cytochrome-c reductase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in aerobic respiration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular respiration IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrial respiratory chain complex III assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane EXP
Inferred from Experiment
more info
 PubMed 
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane TAS
Traceable Author Statement
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
part_of respiratory chain complex III IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of respiratory chain complex III IDA
Inferred from Direct Assay
more info
 PubMed 
part_of respiratory chain complex III IEA
Inferred from Electronic Annotation
more info
  
part_of respiratory chain complex III IPI
Inferred from Physical Interaction
more info
 PubMed 
Preferred Names
ubiquinol--cytochrome-c reductase subunit 9
NP_011699.1
  • Subunit 9 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    859063..859476 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181312.1 → NP_011699.1  ubiquinol--cytochrome-c reductase subunit 9

    See identical proteins and their annotated locations for NP_011699.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUW6, P22289
    Conserved Domains (1) summary
    pfam05365
    Location:4 → 56
    UCR_UQCRX_QCR9; Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P22289.2

Gene LinkOut

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