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PSD2 phosphatidylserine decarboxylase 2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853080, updated on 29-Jun-2024

Summary

Gene symbol
PSD2
Gene description
phosphatidylserine decarboxylase 2
Primary source
FungiDB:YGR170W
Locus tag
YGR170W
See related
SGD:S000003402; AllianceGenome:SGD:S000003402; VEuPathDB:YGR170W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables phosphatidylserine decarboxylase activity. Involved in phosphatidylcholine biosynthetic process. Located in endosome. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See PSD2 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (837142..840558)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene pseudouridine synthase PUS6 Neighboring gene Lso2p Neighboring gene methionine--tRNA ligase MSM1 Neighboring gene transporter YIP1

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables carboxy-lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylserine decarboxylase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylserine decarboxylase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in glycerophospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphatidylcholine biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in phosphatidylethanolamine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in protein autoprocessing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi stack IEA
Inferred from Electronic Annotation
more info
 
located_in endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
phosphatidylserine decarboxylase 2
NP_011686.1
  • Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes; converts phosphatidylserine to phosphatidylethanolamine; controls vacuolar membrane phospholipid content by regulating phospholipids in compartments that will eventually give rise to the vacuole; loss of Psd2p causes a specific reduction in vacuolar membrane PE levels while total PE levels are not significantly affected

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    837142..840558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181299.1NP_011686.1  TPA: phosphatidylserine decarboxylase 2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011686.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUV4, P53037
    UniProtKB/TrEMBL
    A0A8H4C0K0, B3LI60, C7GQ77, N1P3V1
    Conserved Domains (3) summary
    cd00030
    Location:1986
    C2; C2 domain
    PLN02964
    Location:5231079
    PLN02964; phosphatidylserine decarboxylase
    NF033845
    Location:276453
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB