Format

Send to:

Choose Destination

PTI1 cleavage polyadenylation factor subunit PTI1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853060, updated on 1-Nov-2019

Summary

Gene symbol
PTI1
Gene description
cleavage polyadenylation factor subunit PTI1
Primary source
SGD:S000003388
Locus tag
YGR156W
Gene type
protein coding
RNA name
cleavage polyadenylation factor subunit PTI1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See PTI1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (800546..801823)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene omega-class glutathione transferase Neighboring gene cystathionine beta-synthase CYS4 Neighboring gene phosphatidylethanolamine N-methyltransferase Neighboring gene exosome non-catalytic core subunit MTR3

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
contributes_to RNA binding IC
Inferred by Curator
more info
PubMed 
mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
mRNA 3'-end processing IEA
Inferred from Electronic Annotation
more info
 
mRNA polyadenylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
pre-mRNA cleavage required for polyadenylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
pre-mRNA cleavage required for polyadenylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
snoRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
termination of RNA polymerase II transcription, exosome-dependent IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
mRNA cleavage and polyadenylation specificity factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mRNA cleavage and polyadenylation specificity factor complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleus HDA PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cleavage polyadenylation factor subunit PTI1
NP_011672.1
  • Essential component of CPF (cleavage and polyadenylation factor); involved in 3' end formation of snoRNA and mRNA; interacts directly with Pta1p; relocalizes to the cytosol in response to hypoxia; similar to mammalian Cleavage-Stimulation Factor CstF-64

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    800546..801823
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181285.1NP_011672.1  TPA: cleavage polyadenylation factor subunit PTI1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011672.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P39927
    Conserved Domains (3) summary
    smart00360
    Location:2190
    RRM; RNA recognition motif
    pfam14327
    Location:185255
    CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2
    cl25887
    Location:306413
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
Support Center