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BTN2 Btn2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853043, updated on 18-Jan-2023

Summary

Gene symbol
BTN2
Gene description
Btn2p
Primary source
SGD:S000003374
Locus tag
YGR142W
See related
AllianceGenome:SGD:S000003374
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables SNARE binding activity; chaperone binding activity; and protein sequestering activity. Involved in several processes, including protein localization to nucleus; regulation of pH; and retrograde transport, endosome to Golgi. Located in several cellular components, including late endosome; nuclear periphery; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See BTN2 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (772454..773686)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Cbf2p Neighboring gene Vps62p Neighboring gene tRNA-Ala Neighboring gene beta-glucan synthesis-associated protein SKN1

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables SNARE binding IDA
Inferred from Direct Assay
more info
PubMed 
enables SNARE binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables chaperone binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein sequestering activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in amino acid transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intracellular protein transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intracellular protein transport IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in positive regulation of cell growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein folding IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in protein folding IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein folding IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in protein localization to nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein localization to nucleus IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in regulation of pH IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retrograde transport, endosome to Golgi IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in late endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in late endosome IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear periphery IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Btn2p
NP_011658.3
  • v-SNARE binding protein; facilitates specific protein retrieval from a late endosome to the Golgi; modulates arginine uptake, possible role in mediating pH homeostasis between the vacuole and plasma membrane H(+)-ATPase; contributes to prion curing; preferentially expressed after severe ethanol stress, involved in clearance of denatured proteins caused by severe ethanol stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    772454..773686
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181271.3NP_011658.3  TPA: Btn2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011658.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUS2, P53286
    UniProtKB/TrEMBL
    A0A8H4C2X7
    Conserved Domains (1) summary
    PTZ00121
    Location:262402
    PTZ00121; MAEBL; Provisional