Format

Send to:

Choose Destination

ATCAY ATCAY kinesin light chain interacting caytaxin [ Homo sapiens (human) ]

Gene ID: 85300, updated on 24-Nov-2020

Summary

Official Symbol
ATCAYprovided by HGNC
Official Full Name
ATCAY kinesin light chain interacting caytaxinprovided by HGNC
Primary source
HGNC:HGNC:779
See related
Ensembl:ENSG00000167654 MIM:608179
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CLAC; BNIP-H
Summary
This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules. Mutations in this gene are associated with cerebellar ataxia, Cayman type. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward brain (RPKM 41.1) See more
Orthologs

Genomic context

See ATCAY in Genome Data Viewer
Location:
19p13.3
Exon count:
13
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (3880685..3928082)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (3880618..3928080)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 13254 Neighboring gene ferritin light chain pseudogene 5 Neighboring gene RNA, 7SL, cytoplasmic 202, pseudogene Neighboring gene nicotinamide riboside kinase 2 Neighboring gene death associated protein kinase 3 Neighboring gene microRNA 637

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1872

Gene Ontology Provided by GOA

Function Evidence Code Pubs
exopolyphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
kinesin binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion distribution ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of glutamate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
neuron projection development ISS
Inferred from Sequence or Structural Similarity
more info
 
polyphosphate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of protein localization IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
axon ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
dendrite ISS
Inferred from Sequence or Structural Similarity
more info
 
growth cone IEA
Inferred from Electronic Annotation
more info
 
mitochondrial membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
NOT colocalizes_with mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
neuron projection terminus IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
presynapse IEA
Inferred from Electronic Annotation
more info
 
synapse ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
caytaxin
Names
ATCAY, caytaxin
BNIP-2-homolgy
BNIP-2-homology
Cayman ataxia
ataxia cayman type protein
ataxia cerebellar Cayman type

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012638.1 RefSeqGene

    Range
    5001..52463
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_033064.5NP_149053.1  caytaxin

    See identical proteins and their annotated locations for NP_149053.1

    Status: REVIEWED

    Source sequence(s)
    AC011488
    Consensus CDS
    CCDS45923.1
    UniProtKB/Swiss-Prot
    Q86WG3
    UniProtKB/TrEMBL
    A0A0S2Z5T8
    Related
    ENSP00000390941.1, ENST00000450849.7
    Conserved Domains (2) summary
    pfam12496
    Location:59187
    BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
    pfam13716
    Location:189314
    CRAL_TRIO_2; Divergent CRAL/TRIO domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    3880685..3928082
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center