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NOP7 mRNA-binding ribosome synthesis protein NOP7 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852995, updated on 18-Sep-2024

Summary

Official Symbol
NOP7
Official Full Name
mRNA-binding ribosome synthesis protein NOP7
Primary source
SGD:S000003335
Locus tag
YGR103W
See related
AllianceGenome:SGD:S000003335; FungiDB:YGR103W; VEuPathDB:YGR103W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YPH1
Summary
Enables large ribosomal subunit rRNA binding activity. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and ribosomal large subunit biogenesis. Located in nucleolus. Part of PeBoW complex and preribosome, large subunit precursor. Orthologous to human PES1 (pescadillo ribosomal biogenesis factor 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See NOP7 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (695417..697234)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene rhomboid protease PCP1 Neighboring gene glutamyl-tRNA(Gln) amidotransferase subunit F Neighboring gene Srb5p Neighboring gene Vma21p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables mRNA binding HDA PubMed 
enables ribonucleoprotein complex binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of PeBoW complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of PeBoW complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of PeBoW complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
PubMed 
part_of preribosome, large subunit precursor IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mRNA-binding ribosome synthesis protein NOP7
NP_011617.1
  • Component of several different pre-ribosomal particles; forms a complex with Ytm1p and Erb1p that is required for maturation of the large ribosomal subunit; required for exit from G<sub>0</sub> and the initiation of cell proliferation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    695417..697234
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181232.1NP_011617.1  TPA: mRNA-binding ribosome synthesis protein NOP7 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011617.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZV85, D6VUN5, P53261
    UniProtKB/TrEMBL
    B3LIC3, C7GWW0, C8Z8Z6, G2WEI8, N1P3N2
    Conserved Domains (1) summary
    COG5163
    Location:1605
    NOP7; Protein required for biogenesis of the 60S ribosomal subunit [Translation, ribosomal structure and biogenesis]