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RRP46 exosome non-catalytic core subunit RRP46 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852987, updated on 9-Sep-2018

Summary

Gene symbol
RRP46
Gene description
exosome non-catalytic core subunit RRP46
Primary source
SGD:S000003327
Locus tag
YGR095C
Gene type
protein coding
RNA name
exosome non-catalytic core subunit RRP46
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See RRP46 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (675671..676342, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Drn1p Neighboring gene valine--tRNA ligase Neighboring gene thiamine transporter TPC1 Neighboring gene Ask10p

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
U4 snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
PubMed 
ncRNA 3'-end processing IC
Inferred by Curator
more info
PubMed 
nonfunctional rRNA decay IC
Inferred by Curator
more info
PubMed 
nuclear mRNA surveillance IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear polyadenylation-dependent mRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
nuclear polyadenylation-dependent rRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
nuclear polyadenylation-dependent tRNA catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay IC
Inferred by Curator
more info
PubMed 
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' IC
Inferred by Curator
more info
PubMed 
nuclear-transcribed mRNA catabolic process, non-stop decay IC
Inferred by Curator
more info
PubMed 
polyadenylation-dependent snoRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
polyadenylation-dependent snoRNA 3'-end processing IC
Inferred by Curator
more info
PubMed 
rRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
rRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasmic exosome (RNase complex) IDA
Inferred from Direct Assay
more info
PubMed 
exosome (RNase complex) IEA
Inferred from Electronic Annotation
more info
 
nuclear exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear exosome (RNase complex) IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleolus IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
exosome non-catalytic core subunit RRP46
NP_011609.2
  • Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp46p (EXOSC5)

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    675671..676342 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181224.1NP_011609.2  TPA: exosome non-catalytic core subunit RRP46 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011609.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53256
    Conserved Domains (1) summary
    cd11372
    Location:4210
    RNase_PH_RRP46; RRP46 subunit of eukaryotic exosome
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