U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CTT1 catalase T [ Saccharomyces cerevisiae S288C ]

Gene ID: 852979, updated on 9-Dec-2024

Summary

Official Symbol
CTT1
Official Full Name
catalase T
Primary source
SGD:S000003320
Locus tag
YGR088W
See related
AllianceGenome:SGD:S000003320; FungiDB:YGR088W; VEuPathDB:YGR088W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SPS101
Summary
Enables catalase activity. Involved in response to reactive oxygen species. Located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including acatalasia; eye disease (multiple); lung disease (multiple); osteonecrosis; and pseudoxanthoma elasticum. Orthologous to human CAT (catalase). [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See CTT1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (654634..656322)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene indolepyruvate decarboxylase 6 Neighboring gene Nnf2p Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables catalase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables catalase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables catalase activity IEA
Inferred from Electronic Annotation
more info
 
enables heme binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables peroxidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular oxidant detoxification IEA
Inferred from Electronic Annotation
more info
 
involved_in hydrogen peroxide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in hydrogen peroxide catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in response to hydrogen peroxide IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 
involved_in response to reactive oxygen species IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
catalase T
NP_011602.2
  • Cytosolic catalase T; has a role in protection from oxidative damage by hydrogen peroxide

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    654634..656322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181217.1NP_011602.2  TPA: catalase T [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011602.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUM0, P06115
    UniProtKB/TrEMBL
    C8Z8Y2, N1P3Y8
    Conserved Domains (1) summary
    cd08157
    Location:41541
    catalase_fungal; Fungal catalases similar to yeast catalases A and T