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TIM21 Tim21p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852921, updated on 22-Sep-2022

Summary

Gene symbol
TIM21
Gene description
Tim21p
Primary source
SGD:S000003265
Locus tag
YGR033C
See related
AllianceGenome:SGD:S000003265
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in protein import into mitochondrial matrix. Located in mitochondrion. Part of TIM23 mitochondrial import inner membrane translocase complex. Orthologous to human TIMM21 (translocase of inner mitochondrial membrane 21). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See TIM21 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (554248..554967, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Imo32p Neighboring gene Nag1p Neighboring gene 1,3-beta-glucan synthase GSC2 Neighboring gene ribosomal 60S subunit protein L26B Neighboring gene uncharacterized protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in protein import into mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein import into mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 
involved_in protein import into mitochondrial matrix IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Tim21p
NP_011547.3
  • Nonessential component of the TIM23 complex; interacts with the Translocase of the Outer Mitochondrial membrane (TOM complex) and with respiratory enzymes; may regulate the Translocase of the Inner Mitochondrial membrane (TIM23 complex) activity

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    554248..554967 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181162.3NP_011547.3  TPA: Tim21p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011547.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53220, Q45U51
    UniProtKB/TrEMBL
    N1P233
    Conserved Domains (1) summary
    pfam08294
    Location:67219
    TIM21