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EAT1 putative hydrolase [ Saccharomyces cerevisiae S288C ]

Gene ID: 852898, updated on 5-Jul-2025
Official Symbol
EAT1
Official Full Name
putative hydrolase
Primary source
SGD:S000003247
Locus tag
YGR015C
See related
AllianceGenome:SGD:S000003247; FungiDB:YGR015C; VEuPathDB:YGR015C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables C-acetyltransferase activity. Predicted to be involved in lipid metabolic process. Located in mitochondrion. Orthologous to human ABHD11 (abhydrolase domain containing 11). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See EAT1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (521090..522076, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Snu71p Neighboring gene Msb2p Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Ethyl acetate production by the elusive alcohol acetyltransferase from yeast. Kruis AJ, et al. Metab Eng, 2017 May. PMID 28356220
  2. Polygenic Analysis in Absence of Major Effector ATF1 Unveils Novel Components in Yeast Flavor Ester Biosynthesis. Holt S, et al. mBio, 2018 Aug 28. PMID 30154260, Free PMC Article
  3. Contribution of Eat1 and Other Alcohol Acyltransferases to Ester Production in Saccharomyces cerevisiae. Kruis AJ, et al. Front Microbiol, 2018. PMID 30622529, Free PMC Article
  4. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Willingham S, et al. Science, 2003 Dec 5. PMID 14657499
  5. Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress. Jaworek W, et al. J Biol Chem, 2022 Oct. PMID 36115461, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables C-acetyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables acetyl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables carboxylic ester hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
putative hydrolase
NP_011529.1
  • Ethanol acetyltransferase; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    521090..522076 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181144.1 → NP_011529.1  TPA: putative hydrolase

    See identical proteins and their annotated locations for NP_011529.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUF1, P53208
    UniProtKB/TrEMBL
    A6ZV06, B3LIK2, C7GK84, C8Z8Q9, G2WEA7, N1P3E8
    Conserved Domains (1) summary
    pfam00561
    Location:39 → 309
    Abhydrolase_1; alpha/beta hydrolase fold
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53208.1

Gene LinkOut

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