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CDH1 Cdh1p [ Saccharomyces cerevisiae S288c ]

Gene ID: 852881, updated on 5-Mar-2017
Gene symbol
CDH1
Gene description
Cdh1p
Primary source
SGD:S000002971
Locus tag
YGL003C
Gene type
protein coding
RNA name
Cdh1p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HCT1
See CDH1 in Map Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (492474..494174, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Golgi transport complex subunit COG7 Neighboring gene Rpn14p Neighboring gene Erp6p Neighboring gene sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
anaphase-promoting complex binding IDA
Inferred from Direct Assay
more info
PubMed 
anaphase-promoting complex binding IEA
Inferred from Electronic Annotation
more info
 
anaphase-promoting complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
cyclin binding IDA
Inferred from Direct Assay
more info
PubMed 
ubiquitin-protein transferase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
ubiquitin-protein transferase activator activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
anaphase-promoting complex IPI
Inferred from Physical Interaction
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Cdh1p
NP_011512.1
  • Activator of anaphase-promoting complex/cyclosome (APC/C); antagonist of the spindle assembly checkpoint; directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including: Cdc20p, Ase1p, Cin8p, Fin1p and Clb5p; partially active in metaphase, and fully active in anaphase; cell-cycle regulated

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    492474..494174 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180868.1NP_011512.1  TPA: Cdh1p [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_011512.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53197
    Conserved Domains (3) summary
    COG2319
    Location:267565
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:305342
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:269543
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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