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CGR1 Cgr1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852854, updated on 6-Jul-2026
Official Symbol
CGR1
Official Full Name
Cgr1p
Primary source
SGD:S000002997
Locus tag
YGL029W
See related
AllianceGenome:SGD:S000002997; FungiDB:YGL029W; VEuPathDB:YGL029W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in rRNA processing. Located in nucleolus. Part of preribosome, large subunit precursor. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See CGR1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (440063..440425)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein eL24 RPL24A Neighboring gene 60S ribosomal protein eL30 RPL30 Neighboring gene tRNA-Phe Neighboring gene putative glucan endo-1,3-beta-D-glucosidase

Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cgr1p, a novel nucleolar protein encoded by Saccharomyces cerevisiae orf YGL0292w. Sun J, et al. Curr Microbiol, 2001 Jan. PMID 11116400
  2. Molecular cloning of cgrA, the gene encoding the Aspergillus nidulans ortholog of Saccharomyces cerevisiae CGR1. Sun J, et al. Curr Microbiol, 2001 Jun. PMID 11381331
  3. Identification of a role for Saccharomyces cerevisiae Cgr1p in pre-rRNA processing and 60S ribosome subunit synthesis. Moy TI, et al. Microbiology (Reading), 2002 Apr. PMID 11932453
  4. Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae. Caba E, et al. Mutat Res, 2005 Aug 4. PMID 15878181
  5. Differential subcellular localization of ribosomal protein L7 paralogs in Saccharomyces cerevisiae. Kim TY, et al. Mol Cells, 2009 May 31. PMID 19466602

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in rRNA processing IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in ribosome biogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
part_of preribosome, large subunit precursor HDA PubMed 
Preferred Names
Cgr1p
NP_011486.1
  • Protein involved in nucleolar integrity and processing of pre-rRNA; has a role in processing rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress; relocalizes from nucleus to nucleolus upon DNA replication stress

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    440063..440425
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180894.1 → NP_011486.1  Cgr1p

    See identical proteins and their annotated locations for NP_011486.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUA9, P53188
    UniProtKB/TrEMBL
    B3LIP2
    Conserved Domains (1) summary
    pfam03879
    Location:12 → 119
    Cgr1; Cgr1 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53188.1

Gene LinkOut

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