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RPL7A ribosomal 60S subunit protein L7A [ Saccharomyces cerevisiae S288c ]

Gene ID: 852804, updated on 17-Feb-2017
Gene symbol
RPL7A
Gene description
ribosomal 60S subunit protein L7A
Primary source
SGD:S000003044
Locus tag
YGL076C
Gene type
protein coding
RNA name
ribosomal 60S subunit protein L7A
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See RPL7A in Map Viewer
Location:
chromosome: VII
Exon count:
3
Sequence:
Chromosome: VII; NC_001139.9 (364335..365996, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene RNA-dependent ATPase DBP3 Neighboring gene Hnm1p Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Mps2p

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
structural constituent of ribosome IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
cytoplasmic translation IDA
Inferred from Direct Assay
more info
PubMed 
maturation of LSU-rRNA IMP
Inferred from Mutant Phenotype
more info
PubMed 
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
 
ribosomal large subunit biogenesis IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
intracellular ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
PubMed 
ribosome IEA
Inferred from Electronic Annotation
more info
 
Names
ribosomal 60S subunit protein L7A
NP_011439.1
  • Ribosomal 60S subunit protein L7A; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2); binds to Domain II of 25S and 5.8S rRNAs; homologous to mammalian ribosomal protein L7 and bacterial L30; RPL7A has a paralog, RPL7B, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    364335..365996 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180941.1NP_011439.1  TPA: ribosomal 60S subunit protein L7A [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_011439.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P05737
    Conserved Domains (3) summary
    cd01657
    Location:83244
    Ribosomal_L7_archeal_euk; Ribosomal protein L7, which is found in archaea and eukaryotes but not in prokaryotes, binds domain II of the 23S rRNA as well as the 5S rRNA and is one of five ribosomal proteins that mediate the interactions 5S rRNA makes with the ribosome. The ...
    TIGR01310
    Location:10244
    uL30_euk; 60S ribosomal protein uL30, eukaryotic form
    pfam08079
    Location:1181
    Ribosomal_L30_N; Ribosomal L30 N-terminal domain
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