Format

Send to:

Choose Destination

KRTAP9-4 keratin associated protein 9-4 [ Homo sapiens (human) ]

Gene ID: 85280, updated on 12-Oct-2019

Summary

Official Symbol
KRTAP9-4provided by HGNC
Official Full Name
keratin associated protein 9-4provided by HGNC
Primary source
HGNC:HGNC:18902
See related
Ensembl:ENSG00000241595
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KAP9.4; KRTAP9.4
Summary
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]
Orthologs

Genomic context

See KRTAP9-4 in Genome Data Viewer
Location:
17q21.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (41249687..41250653)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (39405939..39406905)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene keratin associated protein 9-3 Neighboring gene keratin associated protein 9-8 Neighboring gene keratin associated protein 9-9 Neighboring gene keratin associated protein 9-6

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Developmental Biology, organism-specific biosystem (from REACTOME)
    Developmental Biology, organism-specific biosystemAs a first step towards capturing the array of processes by which a fertilized egg gives rise to the diverse tissues of the body, examples of three kinds of processes have been annotated. These are a...
  • Keratinization, organism-specific biosystem (from REACTOME)
    Keratinization, organism-specific biosystemKeratins are the major structural protein of vertebrate epidermis, constituting up to 85% of a fully differentiated keratinocyte (Fuchs 1995). Keratins belong to a superfamily of intermediate filamen...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
keratinization TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytosol TAS
Traceable Author Statement
more info
 
keratin filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
keratin-associated protein 9-4
Names
keratin-associated protein 9.4
ultrahigh sulfur keratin-associated protein 9.4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033191.3NP_149461.2  keratin-associated protein 9-4

    See identical proteins and their annotated locations for NP_149461.2

    Status: REVIEWED

    Source sequence(s)
    AC006070
    Consensus CDS
    CCDS11386.1
    UniProtKB/Swiss-Prot
    Q9BYQ2
    Related
    ENSP00000334922.2, ENST00000334109.3
    Conserved Domains (1) summary
    pfam13885
    Location:3784
    Keratin_B2_2; Keratin, high sulfur B2 protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    41249687..41250653
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NW_003871092.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    46203..47169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_2

Genomic

  1. NW_003871093.1 Reference GRCh38.p13 ALT_REF_LOCI_2

    Range
    56457..57423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center