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TAF6 TATA-binding protein-associated factor TAF6 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852766, updated on 11-Jun-2025
Official Symbol
TAF6
Official Full Name
TATA-binding protein-associated factor TAF6
Primary source
SGD:S000003080
Locus tag
YGL112C
See related
AllianceGenome:SGD:S000003080; FungiDB:YGL112C; VEuPathDB:YGL112C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
TAF60
Summary
Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; chromatin binding activity; and molecular adaptor activity. Involved in RNA polymerase II preinitiation complex assembly; chromatin organization; and positive regulation of DNA-templated transcription initiation. Located in cytosol and nucleus. Part of SAGA complex; SLIK (SAGA-like) complex; and transcription factor TFIID complex. Orthologous to several human genes including TAF6 (TATA-box binding protein associated factor 6). [provided by Alliance of Genome Resources, Jun 2025]
Orthologs
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See TAF6 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (298178..299728, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Sld3p Neighboring gene ribosome biosynthesis protein NSA1 Neighboring gene Cue3p

Genomic Sequence:
NC_001139.9
Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by SGD

Component Evidence Code Pubs
part_of SAGA complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of SAGA complex IEA
Inferred from Electronic Annotation
more info
 
part_of SLIK (SAGA-like) complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of SLIK (SAGA-like) complex IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of transcription factor TFIID complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of transcription factor TFIID complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
TATA-binding protein-associated factor TAF6
NP_011403.1
  • Subunit (60 kDa) of TFIID and SAGA complexes; involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4; relocalizes to the cytosol in response to hypoxia

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    298178..299728 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180977.1NP_011403.1  TPA: TATA-binding protein-associated factor TAF6 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011403.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VU35, P53040
    UniProtKB/TrEMBL
    A6ZU70, B3LHH5, C7GM06, C8Z8D8, N1P9P2
    Conserved Domains (1) summary
    COG5095
    Location:6513
    TAF6; Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA) [Transcription]