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SPO74 Spo74p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852705, updated on 5-Jul-2025
Official Symbol
SPO74
Official Full Name
Spo74p
Primary source
SGD:S000003138
Locus tag
YGL170C
See related
AllianceGenome:SGD:S000003138; FungiDB:YGL170C; VEuPathDB:YGL170C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables structural molecule activity. Involved in ascospore formation. Located in meiotic spindle pole body. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See SPO74 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (184153..185394, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene FG-nucleoporin NUP49 Neighboring gene RNA-dependent ATPase ROK1 Neighboring gene tRNA-Lys Neighboring gene threonylcarbamoyladenylate synthase

Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Spore number control and breeding in Saccharomyces cerevisiae: a key role for a self-organizing system. Taxis C, et al. J Cell Biol, 2005 Nov 21. PMID 16286509, Free PMC Article
  2. Membrane assembly modulates the stability of the meiotic spindle-pole body. Mathieson EM, et al. J Cell Sci, 2010 Jul 15. PMID 20592185, Free PMC Article
  3. Regulation of spindle pole function by an intermediary metabolite. Nickas ME, et al. Mol Biol Cell, 2004 Jun. PMID 15034143, Free PMC Article
  4. Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae. Nickas ME, et al. Eukaryot Cell, 2003 Jun. PMID 12796288, Free PMC Article
  5. A refined two-hybrid system reveals that SCF(Cdc4)-dependent degradation of Swi5 contributes to the regulatory mechanism of S-phase entry. Kishi T, et al. Proc Natl Acad Sci U S A, 2008 Sep 23. PMID 18787112, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural molecule activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural molecule activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in ascospore formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sporulation resulting in formation of a cellular spore IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in meiotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in meiotic spindle pole body IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in spindle pole body HDA PubMed 
located_in spindle pole body IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
Spo74p
NP_011345.3
  • Component of the meiotic outer plaque of the spindle pole body; involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    184153..185394 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181035.3 → NP_011345.3  TPA: Spo74p

    See identical proteins and their annotated locations for NP_011345.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTY2, E9P8T5, P45819
    UniProtKB/TrEMBL
    A6ZU16, N1P2W7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P45819.1

Gene LinkOut

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