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MND1 Mnd1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852692, updated on 18-Jan-2023

Summary

Gene symbol
MND1
Gene description
Mnd1p
Primary source
SGD:S000003151
Locus tag
YGL183C
See related
AllianceGenome:SGD:S000003151
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables double-stranded DNA binding activity. Involved in reciprocal meiotic recombination. Located in condensed nuclear chromosome. Orthologous to human MND1 (meiotic nuclear divisions 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See MND1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
2
Sequence:
Chromosome: VII; NC_001139.9 (156543..157285, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene putative hydroxyacid dehydrogenase Neighboring gene cystathionine beta-lyase STR3 Neighboring gene Gts1p Neighboring gene serine/threonine protein kinase ATG1

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables recombinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
 
involved_in homologous chromosome pairing at meiosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in meiotic joint molecule formation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in meiotic strand invasion involved in reciprocal meiotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in nucleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in reciprocal meiotic recombination IEA
Inferred from Electronic Annotation
more info
 
involved_in reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of DNA recombinase auxiliary factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in condensed nuclear chromosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in condensed nuclear chromosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Mnd1p
NP_011332.2
  • Protein required for recombination and meiotic nuclear division; forms a complex with Hop2p, which is involved in chromosome pairing and repair of meiotic double-strand breaks

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    156543..157285 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181048.1NP_011332.2  TPA: Mnd1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011332.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTX1, P53102
    UniProtKB/TrEMBL
    G2WDS4
    Conserved Domains (1) summary
    COG5124
    Location:8219
    COG5124; Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only]