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SDS24 Sds24p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852515, updated on 15-Mar-2026
Official Symbol
SDS24
Official Full Name
Sds24p
Primary source
SGD:S000000418
Locus tag
YBR214W
See related
AllianceGenome:SGD:S000000418; FungiDB:YBR214W; VEuPathDB:YBR214W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable protein serine/threonine phosphatase inhibitor activity. Involved in endocytosis and septum digestion after cytokinesis. Located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See SDS24 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (651415..652998)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Ngr1p Neighboring gene bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase MET8 Neighboring gene Hpc2p Neighboring gene Ybp1p

Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Functional conservation between fission yeast moc1/sds23 and its two orthologs, budding yeast SDS23 and SDS24, and phenotypic differences in their disruptants. Goldar MM, et al. Biosci Biotechnol Biochem, 2005 Jul. PMID 16041152
  2. Identification of phosphatase 2A-like Sit4-mediated signalling and ubiquitin-dependent protein sorting as modulators of caffeine sensitivity in S. cerevisiae. Hood-DeGrenier JK. Yeast, 2011 Mar. PMID 21360731
  3. SAC3 may link nuclear protein export to cell cycle progression. Jones AL, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10716708, Free PMC Article
  4. Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid-phase endocytosis. Wiederkehr A, et al. Yeast, 2001 Jun. PMID 11378903
  5. Reduced Glucose Sensation Can Increase the Fitness of Saccharomyces cerevisiae Lacking Mitochondrial DNA. Akdoğan E, et al. PLoS One, 2016. PMID 26751567, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein serine/threonine phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cellular response to glucose starvation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to glucose starvation IEA
Inferred from Electronic Annotation
more info
  
involved_in endocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of mitotic metaphase/anaphase transition IEA
Inferred from Electronic Annotation
more info
  
involved_in septum digestion after cytokinesis IEA
Inferred from Electronic Annotation
more info
  
involved_in septum digestion after cytokinesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol HDA PubMed 
Preferred Names
Sds24p
NP_009773.1
  • Protein involved in cell separation during budding; one of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; may play an indirect role in fluid-phase endocytosis; protein abundance increases in response to DNA replication stress; SDS24 has a paralog, SDS23, that arose from the whole genome duplication

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    651415..652998
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178562.1 → NP_009773.1  Sds24p

    See identical proteins and their annotated locations for NP_009773.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZLF4, D6VQL0, P38314
    UniProtKB/TrEMBL
    B3LMU6, B5VEG5, D3UEW0, G2W9L7, N1P8P5
    Conserved Domains (3) summary
    COG0517
    Location:114 → 247
    CBS; CBS domain [Signal transduction mechanisms]
    cd02205
    Location:203 → 279
    CBS_pair_SF; CBS repeat [structural motif]
    cl15354
    Location:203 → 331
    CBS_pair_SF; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38314.1

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