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CSH1 mannosylinositol phosphorylceramide synthase catalytic subunit CSH1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852458, updated on 4-Nov-2018

Summary

Gene symbol
CSH1
Gene description
mannosylinositol phosphorylceramide synthase catalytic subunit CSH1
Primary source
SGD:S000000365
Locus tag
YBR161W
Gene type
protein coding
RNA name
mannosylinositol phosphorylceramide synthase catalytic subunit CSH1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See CSH1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (561634..562764)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene ketoreductase Neighboring gene cyclin-dependent serine/threonine-protein kinase CDC28 Neighboring gene Tos1p Neighboring gene Ysy6p

Pathways from BioSystems

  • sphingolipid biosynthesis (yeast), conserved biosystem (from BIOCYC)
    sphingolipid biosynthesis (yeast), conserved biosystemGeneral Background |FRAME: SPHINGOLIPIDS Sphingolipids| are a class of lipids derived from the unsaturated aliphatic amino alcohol |FRAME: SPHINGOSINE| that are essential components of the plasma me...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mannosyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
glycosphingolipid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
mannosyl-inositol phosphorylceramide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mannosylation IEA
Inferred from Electronic Annotation
more info
 
sphingolipid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
fungal-type vacuole HDA PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane ISM
Inferred from Sequence Model
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
vacuolar membrane IEA
Inferred from Electronic Annotation
more info
 
vacuole IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mannosylinositol phosphorylceramide synthase catalytic subunit CSH1
NP_009719.3
  • Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; forms a complex with regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p; CSH1 has a paralog, SUR1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    561634..562764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178509.3NP_009719.3  TPA: mannosylinositol phosphorylceramide synthase catalytic subunit CSH1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009719.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38287
    Conserved Domains (1) summary
    COG3774
    Location:1332
    OCH1; Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis]
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