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RXT2 Rxt2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852392, updated on 18-Jan-2023

Summary

Gene symbol
RXT2
Gene description
Rxt2p
Primary source
SGD:S000000299
Locus tag
YBR095C
See related
AllianceGenome:SGD:S000000299
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RAF60
Summary
Contributes to histone deacetylase activity. Involved in several processes, including invasive growth in response to glucose limitation; positive regulation of invasive growth in response to glucose limitation; and regulation of gene expression. Located in cytosol and nucleus. Part of Rpd3L complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See RXT2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (434406..435698, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene acid phosphatase PHO5 Neighboring gene putative tubulin tyrosine ligase Neighboring gene uncharacterized protein Neighboring gene ubiquitin-binding serine/threonine protein kinase VPS15

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
contributes_to histone deacetylase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of Clr6 histone deacetylase complex I'' IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of Rpd3L complex HDA PubMed 
part_of Rpd3L complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of Rpd3L complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of Rpd3L-Expanded complex HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Rxt2p
NP_009653.2
  • Component of the histone deacetylase Rpd3L complex; possibly involved in cell fusion and invasive growth; relocalizes to the cytosol in response to hypoxia

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    434406..435698 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178443.1NP_009653.2  TPA: Rxt2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009653.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQ96, P38255
    UniProtKB/TrEMBL
    A0A6C1DNA3, A0A8H4F9C7, N1P848
    Conserved Domains (1) summary
    pfam08595
    Location:62221
    RXT2_N; RXT2-like, N-terminal