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NHP6B high-mobility group nucleosome-binding protein [ Saccharomyces cerevisiae S288c ]

Gene ID: 852386, updated on 5-Mar-2017
Gene symbol
NHP6B
Gene description
high-mobility group nucleosome-binding protein
Primary source
SGD:S000002157
Locus tag
YBR089C-A
Gene type
protein coding
RNA name
high-mobility group nucleosome-binding protein
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YBR090C-A
See NHP6B in Map Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (426190..426489, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene replication factor C subunit 5 Neighboring gene proliferating cell nuclear antigen Neighboring gene hypothetical protein Neighboring gene Tim12p Neighboring gene acid phosphatase PHO3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding, bending IDA
Inferred from Direct Assay
more info
PubMed 
nucleosome binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
chromosome IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
high-mobility group nucleosome-binding protein
NP_009647.2
  • High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6B has a paralog, NHP6A, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    426190..426489 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180058.2NP_009647.2  TPA: high-mobility group nucleosome-binding protein [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_009647.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P11633
    Conserved Domains (2) summary
    COG5648
    Location:199
    NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
    cd01390
    Location:2792
    HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
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