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POL30 proliferating cell nuclear antigen [ Saccharomyces cerevisiae S288C ]

Gene ID: 852385, updated on 7-Jul-2019

Summary

Gene symbol
POL30
Gene description
proliferating cell nuclear antigen
Primary source
SGD:S000000292
Locus tag
YBR088C
Gene type
protein coding
RNA name
proliferating cell nuclear antigen
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See POL30 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (424990..425766, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Ist2p Neighboring gene replication factor C subunit 5 Neighboring gene hypothetical protein Neighboring gene high-mobility group nucleosome-binding protein Neighboring gene Tim12p

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the POL30 gene: The POL30 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA polymerase processivity factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA polymerase processivity factor activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA polymerase processivity factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA repair IEA
Inferred from Electronic Annotation
more info
 
DNA replication IEA
Inferred from Electronic Annotation
more info
 
cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
chromatin silencing at silent mating-type cassette IGI
Inferred from Genetic Interaction
more info
PubMed 
chromatin silencing at silent mating-type cassette IMP
Inferred from Mutant Phenotype
more info
PubMed 
chromatin silencing at telomere IMP
Inferred from Mutant Phenotype
more info
PubMed 
error-free translesion synthesis IGI
Inferred from Genetic Interaction
more info
PubMed 
establishment of mitotic sister chromatid cohesion IGI
Inferred from Genetic Interaction
more info
PubMed 
lagging strand elongation IDA
Inferred from Direct Assay
more info
PubMed 
lagging strand elongation IPI
Inferred from Physical Interaction
more info
PubMed 
leading strand elongation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
leading strand elongation IDA
Inferred from Direct Assay
more info
PubMed 
maintenance of DNA trinucleotide repeats IGI
Inferred from Genetic Interaction
more info
PubMed 
maintenance of DNA trinucleotide repeats IMP
Inferred from Mutant Phenotype
more info
PubMed 
meiotic mismatch repair IGI
Inferred from Genetic Interaction
more info
PubMed 
meiotic mismatch repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
mismatch repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mismatch repair IGI
Inferred from Genetic Interaction
more info
PubMed 
mismatch repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
mismatch repair IPI
Inferred from Physical Interaction
more info
PubMed 
mitotic cell cycle IGI
Inferred from Genetic Interaction
more info
PubMed 
mitotic sister chromatid cohesion IGI
Inferred from Genetic Interaction
more info
PubMed 
mitotic sister chromatid cohesion IPI
Inferred from Physical Interaction
more info
PubMed 
nucleotide-excision repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of exodeoxyribonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands IDA
Inferred from Direct Assay
more info
PubMed 
postreplication repair IGI
Inferred from Genetic Interaction
more info
PubMed 
postreplication repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of DNA replication IEA
Inferred from Electronic Annotation
more info
 
translesion synthesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
PCNA complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
PCNA complex IPI
Inferred from Physical Interaction
more info
PubMed 
chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
replication fork IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
proliferating cell nuclear antigen
NP_009645.1
  • Proliferating cell nuclear antigen (PCNA); functions as the sliding replication clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair; PCNA ubiquitination at K164 plays a crucial role during Okazaki fragment processing

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    424990..425766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178436.1NP_009645.1  TPA: proliferating cell nuclear antigen [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009645.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15873
    Conserved Domains (1) summary
    TIGR00590
    Location:1258
    pcna; proliferating cell nuclear antigen (pcna)
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