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NRG2 Nrg2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852358, updated on 24-Apr-2022

Summary

Gene symbol
NRG2
Gene description
Nrg2p
Primary source
SGD:S000000270
Locus tag
YBR066C
See related
AllianceGenome:SGD:S000000270
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables sequence-specific DNA binding activity. Involved in cell adhesion involved in single-species biofilm formation; negative regulation of pseudohyphal growth; and negative regulation of transcription, DNA-templated. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See NRG2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (370037..370699, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Cnm1p Neighboring gene Ecm2p Neighboring gene putative lipase Neighboring gene branched-chain amino acid permease BAP2

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of PcG protein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Nrg2p
NP_009622.1
  • Transcriptional repressor; mediates glucose repression and negatively regulates filamentous growth; activated in stochastic pulses of nuclear localization in response to low glucose

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    370037..370699 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178414.1NP_009622.1  TPA: Nrg2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009622.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38082
    Conserved Domains (2) summary
    COG5048
    Location:72220
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:155175
    ZF_C2H2; C2H2 Zn finger [structural motif]