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UBP14 ubiquitin-specific protease UBP14 [ Saccharomyces cerevisiae S288c ]

Gene ID: 852349, updated on 5-Mar-2017
Gene symbol
UBP14
Gene description
ubiquitin-specific protease UBP14
Primary source
SGD:S000000262
Locus tag
YBR058C
Gene type
protein coding
RNA name
ubiquitin-specific protease UBP14
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
GID6
See UBP14 in Map Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (353672..356017, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Mum2p Neighboring gene Tsc3p Neighboring gene serine/threonine protein kinase AKL1

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
thiol-dependent ubiquitin-specific protease activity IDA
Inferred from Direct Assay
more info
PubMed 
thiol-dependent ubiquitin-specific protease activity IEA
Inferred from Electronic Annotation
more info
 
thiol-dependent ubiquitinyl hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
negative regulation of gluconeogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
proteasome-mediated ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IC
Inferred by Curator
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
ubiquitin-specific protease UBP14
NP_009614.2
  • Ubiquitin-specific protease; specifically disassembles unanchored ubiquitin chains; involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; similar to human isopeptidase T

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    353672..356017 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178406.1NP_009614.2  TPA: ubiquitin-specific protease UBP14 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_009614.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38237
    Conserved Domains (5) summary
    COG5207
    Location:1781
    UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
    cd02658
    Location:324778
    Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cd14298
    Location:652689
    UBA2_scUBP14_like; UBA2 domain found in Saccharomyces cerevisiae ubiquitin carboxyl-terminal hydrolase 14 (scUBP14) and similar proteins
    pfam02148
    Location:192264
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl21463
    Location:587633
    UBA_like_SF; UBA domain-like superfamily
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