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YRO2 Yro2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852343, updated on 4-Jan-2025

Summary

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Official Symbol
YRO2
Official Full Name
Yro2p
Primary source
SGD:S000000258
Locus tag
YBR054W
See related
AllianceGenome:SGD:S000000258; FungiDB:YBR054W; VEuPathDB:YBR054W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See YRO2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (343101..344135)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene flavodoxin-like fold family protein Neighboring gene uncharacterized protein Neighboring gene U4/U6-U5 snRNP complex subunit PRP6 Neighboring gene tRNA-Leu

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Homologues of archaeal rhodopsins in plants, animals and fungi: structural and functional predications for a putative fungal chaperone protein. Zhai Y, et al. Biochim Biophys Acta, 2001 Apr 2. PMID 11286964
  2. Plasma membrane proteins Yro2 and Mrh1 are required for acetic acid tolerance in Saccharomyces cerevisiae. Takabatake A, et al. Appl Microbiol Biotechnol, 2015 Mar. PMID 25503505
  3. Haa1, a protein homologous to the copper-regulated transcription factor Ace1, is a novel transcriptional activator. Keller G, et al. J Biol Chem, 2001 Oct 19. PMID 11504737
  4. Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis. Bandhakavi S, et al. PLoS One, 2008 Feb 13. PMID 18270585, Free PMC Article
  5. Nuclear localization of Haa1, which is linked to its phosphorylation status, mediates lactic acid tolerance in Saccharomyces cerevisiae. Sugiyama M, et al. Appl Environ Microbiol, 2014 Jun. PMID 24682296, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Yro2 and Mrh1 are involved in tolerance to acetic acid stress.
    Title: Plasma membrane proteins Yro2 and Mrh1 are required for acetic acid tolerance in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cellular bud HDA PubMed 
located_in endoplasmic reticulum HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Yro2p
NP_009610.1
  • Protein with a putative role in response to acid stress; null mutant is sensitive to acetic acid; transcription is regulated by Haa1p and induced in the presence of acetic acid; protein observed in plasma membrane foci in the presence of acetic acid; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    343101..344135
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178402.1 → NP_009610.1  TPA: Yro2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009610.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQ53, P38079
    UniProtKB/TrEMBL
    A6ZKZ7, B3LN95, C7GSU0, G2W959, N1PAR8
    Conserved Domains (1) summary
    COG5524
    Location:4 → 290
    COG5524; Bacteriorhodopsin [Energy production and conversion, Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38079.1

Gene LinkOut

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