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GAL10 bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase [ Saccharomyces cerevisiae S288C ]

Gene ID: 852307, updated on 8-Oct-2017
Gene symbol
GAL10
Gene description
bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase
Primary source
SGD:S000000223
Locus tag
YBR019C
Gene type
protein coding
RNA name
bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See GAL10 in Map Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (276253..278352, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Kap104p Neighboring gene UDP-glucose:hexose-1-phosphate uridylyltransferase Neighboring gene galactokinase Neighboring gene uracil permease

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
UDP-glucose 4-epimerase activity IDA
Inferred from Direct Assay
more info
PubMed 
UDP-glucose 4-epimerase activity IEA
Inferred from Electronic Annotation
more info
 
UDP-glucose 4-epimerase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
aldose 1-epimerase activity IDA
Inferred from Direct Assay
more info
PubMed 
aldose 1-epimerase activity IEA
Inferred from Electronic Annotation
more info
 
carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
isomerase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
galactose catabolic process via UDP-galactose IDA
Inferred from Direct Assay
more info
PubMed 
galactose catabolic process via UDP-galactose IMP
Inferred from Mutant Phenotype
more info
PubMed 
galactose metabolic process IEA
Inferred from Electronic Annotation
more info
 
hexose metabolic process IEA
Inferred from Electronic Annotation
more info
 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
Names
bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase
NP_009575.1
  • UDP-glucose-4-epimerase; catalyzes interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers; human homolog GALE implicated in galactosemia, can complement yeast null mutant

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    276253..278352 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178367.1NP_009575.1  TPA: bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009575.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P04397
    Conserved Domains (2) summary
    cd09019
    Location:376698
    galactose_mutarotase_like; galactose mutarotase_like
    cd05247
    Location:14349
    UDP_G4E_1_SDR_e; UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs
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