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ACH1 acetyl-CoA hydrolase [ Saccharomyces cerevisiae S288C ]

Gene ID: 852266, updated on 9-Dec-2024

Summary

Official Symbol
ACH1
Official Full Name
acetyl-CoA hydrolase
Primary source
SGD:S000000111
Locus tag
YBL015W
See related
AllianceGenome:SGD:S000000111; FungiDB:YBL015W; VEuPathDB:YBL015W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables acetate CoA-transferase activity and acetyl-CoA hydrolase activity. Involved in acetate metabolic process. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See ACH1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (194122..195702)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene type I sorting receptor Neighboring gene mitogen-activated serine/threonine-protein kinase FUS3 Neighboring gene tRNA-Ile Neighboring gene tRNA-Gly

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables acetate CoA-transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables acetate CoA-transferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables acetate CoA-transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acetyl-CoA hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables acetyl-CoA hydrolase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables acetyl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in acetate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in acetate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in acetate metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
acetyl-CoA hydrolase
NP_009538.1
  • Protein with CoA transferase activity; particularly for CoASH transfer from succinyl-CoA to acetate; has minor acetyl-CoA-hydrolase activity; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    194122..195702
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178255.1NP_009538.1  TPA: acetyl-CoA hydrolase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009538.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPY5, P32316
    UniProtKB/TrEMBL
    A6ZKT3, B3LNF3, C7GX95, C8Z3Y1, G2W8Z4, N1P7F3
    Conserved Domains (1) summary
    COG0427
    Location:6519
    ACH1; Acyl-CoA hydrolase [Energy production and conversion]