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RPS8A 40S ribosomal protein eS8 RPS8A [ Saccharomyces cerevisiae S288C ]

Gene ID: 852206, updated on 15-Feb-2026
Official Symbol
RPS8A
Official Full Name
40S ribosomal protein eS8 RPS8A
Primary source
SGD:S000000168
Locus tag
YBL072C
See related
AllianceGenome:SGD:S000000168; FungiDB:YBL072C; VEuPathDB:YBL072C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
A structural constituent of ribosome. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Orthologous to human RPS8 (ribosomal protein S8). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See RPS8A in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (88523..89125, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene U5 snRNP complex subunit AAR2 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Kti11p Neighboring gene uncharacterized protein

Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TFIIA and the transactivator Rap1 cooperate to commit TFIID for transcription initiation. Papai G, et al. Nature, 2010 Jun 17. PMID 20559389, Free PMC Article
  2. Balanced production of ribosome components is required for proper G1/S transition in Saccharomyces cerevisiae. Gómez-Herreros F, et al. J Biol Chem, 2013 Nov 1. PMID 24043628, Free PMC Article
  3. The DEAH-box helicase Dhr1 dissociates U3 from the pre-rRNA to promote formation of the central pseudoknot. Sardana R, et al. PLoS Biol, 2015 Feb. PMID 25710520, Free PMC Article
  4. Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth. Ghalei H, et al. J Cell Biol, 2015 Mar 16. PMID 25778921, Free PMC Article
  5. Dual binding mode of the nascent polypeptide-associated complex reveals a novel universal adapter site on the ribosome. Pech M, et al. J Biol Chem, 2010 Jun 18. PMID 20410297, Free PMC Article

See all (128) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
Inferred from Electronic Annotation
more info
  
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of 90S preribosome HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
40S ribosomal protein eS8 RPS8A
NP_009481.1
  • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S8, no bacterial homolog; RPS8A has a paralog, RPS8B, that arose from the whole genome duplication

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    88523..89125 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178312.1 → NP_009481.1  40S ribosomal protein eS8 RPS8A

    See identical proteins and their annotated locations for NP_009481.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A2TBM0, A2TBP0, D3DM09, P05754, P0CX39, P0CX40, P22801
    UniProtKB/TrEMBL
    A6ZKM8, A6ZR58, B3LNK6, B3LRM0, B5VHM8, C8Z3S1, G2W8T8, G2WD21, N1P719
    Conserved Domains (1) summary
    PTZ00148
    Location:1 → 200
    PTZ00148; 40S ribosomal protein S8; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CX39.1
P0CX40.1

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Research Materials
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