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SFT2 Sft2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852172, updated on 18-Sep-2024

Summary

Official Symbol
SFT2
Official Full Name
Sft2p
Primary source
SGD:S000000198
Locus tag
YBL102W
See related
AllianceGenome:SGD:S000000198; FungiDB:YBL102W; VEuPathDB:YBL102W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in retrograde transport, endosome to Golgi. Located in Golgi membrane and Golgi trans cisterna. Orthologous to several human genes including SFT2D3 (SFT2 domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See SFT2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (24098..24745)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Sea4p Neighboring gene Rtg3p Neighboring gene Ecm21p Neighboring gene uncharacterized protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in retrograde transport, endosome to Golgi IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi trans cisterna IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Sft2p
NP_009448.1
  • Tetra-spanning membrane protein found mostly in the late Golgi; non-essential; can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    24098..24745
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178342.1NP_009448.1  TPA: Sft2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009448.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPQ1, P38166
    UniProtKB/TrEMBL
    A6ZKK2, B3LNN2, B5VDP3, C7GSE3, C8Z3T9, G2W8R2, N1PAX5
    Conserved Domains (1) summary
    COG5102
    Location:7214
    SFT2; Membrane protein involved in ER to Golgi transport [Intracellular trafficking and secretion]