Format

Send to:

Choose Destination

SEA4 Sea4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852170, updated on 5-Sep-2021

Summary

Gene symbol
SEA4
Gene description
Sea4p
Primary source
SGD:S000000200
Locus tag
YBL104C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YBL103C-A
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SEA4 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (18177..21293, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene putative Rab GTPase-binding protein SRO77 Neighboring gene protein kinase C Neighboring gene Rtg3p Neighboring gene Sft2p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cellular response to amino acid starvation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of TOR signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of TORC1 signaling IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Seh1-associated complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in extrinsic component of fungal-type vacuolar membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
 
located_in vacuole IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Sea4p
NP_009446.2
  • Subunit of SEACAT, a subcomplex of the SEA complex; Sea4p, along with Rtc1p and Mtc5p, redundantly inhibit the TORC1 inhibitory role of the Iml1p/SEACIT (Iml1p-Npr2p-Npr3p) subcomplex, a GAP for GTPase Gtr1p (EGOC subunit) in response to amino acid limitation, thereby resulting in activation of TORC1 signaling; SEA is a coatomer-related complex that associates dynamically with the vacuole; contains an N-terminal beta-propeller fold and a C-terminal RING motif

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    18177..21293 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178344.1NP_009446.2  TPA: Sea4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009446.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38164
    Conserved Domains (1) summary
    cl24077
    Location:9431036
    Zn_ribbon_17; Zinc-ribbon, C4HC2 type
Support Center